acute lung injury – Communicable Diseases Research

Xuanfei Baidu Formula attenuates LPS-induced acute lung injury by inhibiting the NF-κB signaling pathway

Article

Published on 2023-01-302022-11-15
Journal: Journal of ethnopharmacology
[Category] 유전자 메커니즘, 진단,

[키워드] Activation acute lung injury ALI model alleviate analysis Analysis attenuate Baidu caused Cell cellular China component Component analysis components Compound COVID-19 COVID-19 patients demonstrated experiment experimental validation Formula in vivo increases in indicated Inflammation ingredient inhibited inhibiting Kyoto lung Lung injury material mechanism of action Mild molecular mechanism network network pharmacology NF-κB pathway NF-κB signaling NF-κB signaling pathway Obstructive Ontology p-NF-κB p65 pathway pharmacological predicted proinflammatory Proteins reduced syndrome target treat Treatment Xuanfei baidu formula.
[DOI] 10.1016/j.jep.2022.115833 PMC 바로가기

Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway

Article

Published on 2023-01-302022-11-16
Journal: Journal of ethnopharmacology
[Category] 신종인플루엔자, 치료기술,

[키워드] acute lung injury analyzed Anti-inflammation Apoptosis approved attenuate BALF Bcl-xL caspase Cell changes China confocal microscope coronavirus COVID-19 declined downstream drug Effect expression fatal complication flow cytometry food Granule H1N1 influenza histological histopathological IL-1β IL-6 immunofluorescence Infectious disease Influenza virus inhibited injection intrinsic investigated Jinhua Qinggan granules LPS lung Lung injury Lungs material mechanism mice Mild mitochondrial apoptotic pathway moderate morbidity and mortality MPO neutrophil Neutrophil apoptosis novel coronavirus disease Nuclear factor kappa-B nuclei p65 pathway pharmacological positive proportion Protein protein concentration protein expression pulmonary inflammation receptor reduced Respiratory disease Respiratory virus infection Signaling signaling pathway significantly staining survival survival rate TLR4 TNF-α Toll-like receptor 4. treated Treatment were assessed were measured
[DOI] 10.1016/j.jep.2022.115763 PMC 바로가기

Ultrafiltration isolation, structure and effects on H1N1-induced acute lung injury of a heteropolysaccharide from Houttuynia cordata

Article

Published on 2022-12-012023-06-23
Journal: International journal of biological macromolecules
[Category] 신종인플루엔자,

[키워드] acute lung injury Houttuynia cordata influenza A virus polysaccharide Structural elucidation Ultrafiltration membrane technology.
[DOI] 10.1016/j.ijbiomac.2022.10.027 PMC 바로가기

H1N1 influenza virus dose dependent induction of dysregulated innate immune responses and STAT1/3 activation are associated with pulmonary immunopathological damage

Article

Published on 2022-12-012023-06-23
Journal: Virulence
[Category] 신종인플루엔자,

[키워드] acute lung injury H1N1 innate immune Stat1 STAT3 Viral pneumonia.
[DOI] 10.1080/21505594.2022.2120951 PMC 바로가기

The potential link between Covid-19 and multiple myeloma: A new saga

Review

Published on 2022-12-012023-07-10
Journal: Immunity, Inflammation and Disease
[Category] COVID19(2023년),

[키워드] acute lung injury acute respiratory distress syndrome COVID-19 multiple myeloma. SARS-CoV-2
[DOI] 10.1002/iid3.701 PMC 바로가기 [Article Type] Review

Therapeutic Potential of 2-Methylquinazolin-4(3H)-one as an Antiviral Agent against Influenza A Virus-Induced Acute Lung Injury in Mice

Article

Published on 2022-11-142023-06-24
Journal: Molecules
[Category] 신종인플루엔자,

[키워드] 2-Methylquinazolin-4(3H)-one acute lung injury antiviral activity influenza A virus Qingdai-Mabo Viral pneumonia.
[DOI] 10.3390/molecules27227857 PMC 바로가기

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice

Article

Published on 2022-11-012022-11-15
Journal: Inflammation research : official journal of the Eu
[Category] 유전자 메커니즘, 진단,

[키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome alleviate Analysis Anti-inflammatory anti-inflammatory property anti-inflammatory response ARDS CFZ Clofazimine coronavirus disease COVID-19 Critical decrease disease Diseases distress down-regulate histological change hyperimmune response IL-1β immune IMPROVE increasingly Infectious disease Inflammatory information inhibit involved lipopolysaccharide LPS lung Lung injury Macrophage macrophages mechanism mice Molecular biology pathway pharmacological mechanism potential molecular profile proliferation protective effect Protein protein expression Proteomic analysis proteomics proteomics. Pulmonary edema Quantitative Signal transduction Signaling significantly survival rate syndrome therapeutic strategy TNF-α
[DOI] 10.1007/s00011-022-01623-w PMC 바로가기

Nitazoxanide and COVID-19: A review

Article

Published on 2022-11-012022-11-15
Journal: Molecular biology reports
[Category] SARS, 치료제,

[키워드] Activation acute lung injury acute respiratory distress acute respiratory distress syndrome addition Anti-inflammatory anti-parasitic drug anti-SARS-CoV-2 Antiviral antiviral activity antiviral property ARDS autophagic cause cell death clinical trial Coronavirus disease 2019 COVID-19 Cytokine storm Cytokines distress drug effective finding IFN immunological in silico in vitro study Infection inflammatory disorders inflammatory reaction inhibit Innate immunity interferon lung mammalian mitigate Multi-organ damage nitazoxanide oxidative stress pathogenesis of SARS-CoV-2 pro-inflammatory cytokines pro-inflammatory cytokines. Prospective Study Protozoa Rapamycin reduce Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 infections severe cases syndrome therapy Treatment triggered viral infections Viral pneumonia
[DOI] 10.1007/s11033-022-07822-2 PMC 바로가기

Ginkgo biloba in the management of the COVID-19 severity

Article

Published on 2022-10-012022-11-15
Journal: Archiv der Pharmazie
[Category] COVID19(2023년), SARS, 변종, 치료제,

Ursolic acid and SARS-CoV-2 infection: a new horizon and perspective

Article

Published on 2022-10-012022-11-15
Journal: Inflammopharmacology
[Category] COVID19(2023년), SARS, 치료제,

[키워드] acute lung injury acute respiratory distress acute respiratory syndrome Anti-inflammatory anti-inflammatory cytokines antioxidant antioxidant effects Antiviral ARDS Complication complications coronavirus COVID-19 Cytokine storm disease-causing disorders dysregulation hyper inflammation immune response Immunity IMPROVE indirect effect inflammatory signaling inhibit lung manifestation mitigate neurological oxidative stress pandemic pandemics. Pathways Perspective pro-inflammatory cytokine pro-inflammatory cytokines progression RAS reactive oxygen specy reduce renin-angiotensin system ROS SARS-CoV-2 SARS-COV-2 infection severe cases syndrome ursolic acid Viral pneumonia
[DOI] 10.1007/s10787-022-01038-3 PMC 바로가기